Opportunity Information: Apply for PAR 27 056
The NIH Institutional Development Award (IDeA) for Clinical and Translational Research (CTR) (P30; clinical trial optional) is a limited-competition grant opportunity designed to strengthen clinical and translational research capacity in IDeA-eligible states, meaning states that have historically received comparatively low levels of NIH funding. The core aim is practical and capacity-focused: help eligible states build the people, systems, and coordinated infrastructure needed to conduct high-quality clinical and translational research that addresses diseases and health challenges that are especially relevant to those states. Applications are solicited under a Notice of Funding Opportunity (NOFO) and will be reviewed through standard NIH peer-review processes, with only the most competitive and meritorious proposals considered for award.
The program supports two distinct but related tracks. The first track, IDeA CTR Development (CTR-D), is aimed at health research organizations within IDeA states that have relatively limited clinical research capacity. CTR-D awards prioritize building the clinical and translational research workforce and improving foundational infrastructure, so that institutions can better support studies, recruit and train investigators and staff, and develop the operational backbone needed for sustained research activity. The second track, IDeA CTR Network (CTR-N), focuses on organizing and strengthening statewide or multi-state networks of health research organizations. CTR-N awards are intended to expand and harmonize existing infrastructure across participating sites, develop the network-wide workforce, enhance the network’s ability to design and run competitive clinical and translational research programs, and coordinate clinical research activities across an entire state or region. In practice, CTR-N is about building a coordinated ecosystem where multiple institutions can work together consistently, rather than operating as isolated pockets of capability.
A major feature of this NOFO is its strict eligibility structure, which is designed to avoid duplication and overlap across states and organizations. Every participating entity in an application must be designated as either a Lead organization or a Partner organization, and no organization is allowed to hold both roles in the same application. All organizations included in the application must be physically located in an IDeA-eligible state. Beyond that, there are strong restrictions on concurrent participation: each IDeA-eligible state may have only one active IDeA-CTR-type award at any given time, where "IDeA-CTR-type" includes the legacy IDeA-CTR mechanism as well as CTR-N and CTR-D awards. Similarly, an individual organization may participate in only one IDeA-CTR-type award at a time, whether as lead, partner, or otherwise involved. The NOFO also prohibits participation by organizations that have an active Clinical and Translational Science Award (CTSA); an organization cannot serve as a lead or partner, or otherwise participate, if it is currently part of an active CTSA. Importantly, these requirements must be met both at the time of submission and at the time of award, and "active" awards include projects in a no-cost extension period.
Lead organizations face an additional threshold requirement that signals readiness to anchor a CTR effort: to apply as the lead, the organization must already have externally funded clinical and translational research. That requirement helps ensure the lead institution has at least a baseline track record and operational maturity to coordinate and manage the proposed CTR activities. Partner organizations must meet a geographic alignment rule: they must be located in the same state as the lead organization or within the same multi-state region, reinforcing the program’s emphasis on building coherent state or regional capacity rather than loosely connected national collaborations.
This NOFO also allows a pathway for continuity and evolution when an organization already leads an active IDeA-CTR-type award. If substantial changes to the CTR are proposed, the current lead organization may submit a new application. If the new application is funded, NIH will administratively end the existing award before the new award begins, which prevents overlapping funding while still allowing a program to pivot or restructure in a significant way.
From an administrative standpoint, the opportunity is offered by the National Institutes of Health as a discretionary grant under funding opportunity number PAR-27-056. It falls under the health funding activity category and is associated with CFDA number 93.859. The eligible applicant types are broad and include various governmental entities (state, county, city/township, special districts), public and private institutions of higher education, independent school districts, certain tribal governments and tribal organizations, public housing authorities/Indian housing authorities, nonprofits (both 501(c)(3) and non-501(c)(3)), for-profit organizations (other than small businesses), small businesses, and other eligible entities, provided they meet the program’s specific IDeA-state and non-overlap rules. The listed original closing date is 2029-05-30, and the NOFO was created on 2026-08-19. The award ceiling and expected number of awards are not specified in the provided summary, which typically means applicants need to consult the full NOFO for budget limits, anticipated award counts, and other submission details.Apply for PAR 27 056
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition: Institutional Development Award (IDeA) for Clinical & Translational Research (CTR) (P30 - CT Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859.
- This funding opportunity was created on 2026-08-19.
- Applicants must submit their applications by 2029-05-30.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: NIH IDeA for Clinical and Translational Research (CTR) (P30; clinical trial optional) - PAR-27-056
What is this funding opportunity?
This is the NIH Institutional Development Award (IDeA) for Clinical and Translational Research (CTR) (P30; clinical trial optional). It is a limited-competition grant opportunity intended to strengthen clinical and translational research capacity in IDeA-eligible states (states that have historically received comparatively low levels of NIH funding).
What is the main purpose of the IDeA CTR program?
The goal is to build practical, capacity-focused capabilities in eligible states by developing the people, systems, and coordinated infrastructure needed to conduct high-quality clinical and translational research. The program emphasizes research that addresses diseases and health challenges especially relevant to those states.
How are applications submitted and reviewed?
Applications are solicited under a Notice of Funding Opportunity (NOFO) and are reviewed through standard NIH peer-review processes. Only the most competitive and meritorious proposals will be considered for award.
What funding opportunity number is associated with this NOFO?
The funding opportunity number is PAR-27-056.
Which NIH mechanism is used for this program?
The mechanism is P30 (clinical trial optional).
What are the two tracks supported under this NOFO?
The program supports two tracks: (1) IDeA CTR Development (CTR-D) and (2) IDeA CTR Network (CTR-N).
What is the CTR-D (IDeA CTR Development) track intended to support?
CTR-D is aimed at health research organizations in IDeA states that have relatively limited clinical research capacity. It prioritizes building the clinical and translational research workforce and improving foundational infrastructure so institutions can better support studies, recruit and train investigators and staff, and develop the operational backbone needed for sustained research activity.
What is the CTR-N (IDeA CTR Network) track intended to support?
CTR-N focuses on organizing and strengthening statewide or multi-state networks of health research organizations. It is intended to expand and harmonize infrastructure across sites, develop a network-wide workforce, enhance the network's ability to design and run competitive clinical and translational research programs, and coordinate clinical research activities across an entire state or region.
What does "limited competition" mean in the context of this opportunity?
Based on the information provided, the opportunity is structured with strict eligibility and participation rules (including state-level and organization-level limits on concurrent awards and prohibitions related to CTSA participation). These requirements narrow who can apply and help prevent duplication and overlap across states and organizations.
Who must be located in an IDeA-eligible state?
All organizations included in the application must be physically located in an IDeA-eligible state.
How are organizations categorized within an application?
Every participating entity must be designated as either a Lead organization or a Partner organization.
Can an organization be both a Lead and a Partner in the same application?
No. An organization cannot hold both roles within the same application.
Are there limits on how many IDeA-CTR-type awards a state can have at once?
Yes. Each IDeA-eligible state may have only one active IDeA-CTR-type award at any given time. "IDeA-CTR-type" includes the legacy IDeA-CTR mechanism as well as CTR-N and CTR-D awards.
Are there limits on how many IDeA-CTR-type awards an organization can participate in at once?
Yes. An individual organization may participate in only one IDeA-CTR-type award at a time, whether as the lead, as a partner, or otherwise involved.
Do the non-overlap rules apply only at submission, or also at award?
They apply at both the time of submission and the time of award.
Does an award in a no-cost extension period count as "active" for eligibility purposes?
Yes. "Active" awards include projects in a no-cost extension period.
Can an organization that is part of a Clinical and Translational Science Award (CTSA) participate?
No. The NOFO prohibits participation by organizations that have an active CTSA. An organization cannot serve as a lead or partner, or otherwise participate, if it is currently part of an active CTSA.
Is there an additional eligibility requirement to apply as the Lead organization?
Yes. To apply as the lead, the organization must already have externally funded clinical and translational research.
Why does the lead organization need externally funded clinical and translational research?
The stated purpose of this threshold requirement is to ensure the lead institution has at least a baseline track record and operational maturity to coordinate and manage the proposed CTR activities.
Where must Partner organizations be located relative to the Lead?
Partner organizations must be located in the same state as the lead organization or within the same multi-state region.
Can a current IDeA-CTR-type awardee submit a new application?
Yes. If an organization already leads an active IDeA-CTR-type award and proposes substantial changes to the CTR, the current lead organization may submit a new application.
What happens if a new application from an existing lead organization is funded while an older IDeA-CTR-type award is still active?
If the new application is funded, NIH will administratively end the existing award before the new award begins, preventing overlapping funding while allowing significant restructuring or pivoting.
What federal assistance listing or CFDA number is associated with this opportunity?
The opportunity is associated with CFDA number 93.859.
What type of grant is this considered?
It is offered by NIH as a discretionary grant and falls under the health funding activity category.
Which applicant types are eligible to apply?
The eligible applicant types listed include governmental entities (state, county, city/township, special districts), public and private institutions of higher education, independent school districts, certain tribal governments and tribal organizations, public housing authorities/Indian housing authorities, nonprofits (501(c)(3) and non-501(c)(3)), for-profit organizations (other than small businesses), small businesses, and other eligible entities, as long as they meet the program's IDeA-state location requirements and strict non-overlap rules.
Does being an eligible entity type automatically mean an organization can apply?
No. In addition to being an eligible applicant type, the organization must meet the specific program rules, including being physically located in an IDeA-eligible state and complying with restrictions that prevent overlap (including the one-award-per-state and one-award-per-organization limits and the CTSA prohibition).
Is the award ceiling provided in the summary?
No. The award ceiling is not specified in the provided summary.
Is the expected number of awards provided in the summary?
No. The expected number of awards is not specified in the provided summary.
What should applicants do if they need budget limits or expected award counts?
Because those details are not included in the provided summary, applicants would typically need to consult the full NOFO for budget limits, anticipated award counts, and other submission requirements.
What is the original closing date shown for this opportunity?
The listed original closing date is 2029-05-30.
When was this NOFO created?
The NOFO was created on 2026-08-19.
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