Opportunity Information: Apply for W81XWH 22 MSRP IIRA
The Department of Defense (DoD), through the U.S. Army Medical Research Acquisition Activity (USAMRAA), offered the Multiple Sclerosis Research Program (MSRP) Investigator-Initiated Research Award (IIRA) under funding opportunity number W81XWH 22 MSRP IIRA. This opportunity is a discretionary research and development award mechanism offered as either a grant or a cooperative agreement, supporting science and technology and other R&D activities aligned with CFDA 12.420. The funding notice was created on April 29, 2022, with an original application closing date of October 3, 2022. The program anticipated making approximately six awards, while the listed award ceiling was shown as 0, which typically indicates that the maximum funding level may be specified elsewhere in the full announcement or depends on the proposed scope and available funds rather than a fixed published cap in the summary record.
The core purpose of the IIRA is to back highly rigorous, high-impact multiple sclerosis (MS) research that can meaningfully advance the field and/or improve patient care. The award is designed for investigator-driven ideas, meaning applicants propose their own research questions and approaches rather than responding to a narrowly defined topic area. Projects can be in any phase of research, which allows everything from foundational and mechanistic work to translational studies, so long as the work is aimed at generating an important contribution to MS research outcomes. A key restriction is that clinical trials are excluded under this mechanism, so studies that would be classified as clinical trials (for example, prospective assignment of human participants to interventions to evaluate effects on health-related outcomes) are not supported through this specific award.
The solicitation emphasizes that strong scientific rationale can come from many sources, reflecting how MS advances often occur: laboratory discoveries, findings emerging from prior clinical trial results, analyses of population-based or epidemiologic datasets, insights derived from a clinician's direct experience treating patients, or even well-documented anecdotal observations that point to a testable hypothesis. Even though the idea can start from varied origins, the bar for evidence is clearly set: applications must include preliminary and/or published data that are directly relevant to MS and to the proposed project. In practical terms, the program is looking for proposals that are not purely speculative. The investigators should be able to show credible groundwork or existing evidence that supports feasibility and makes the case that the planned study can deliver interpretable, impactful results.
Eligibility was described as unrestricted, meaning the opportunity was open to any type of applicant organization, subject to any additional eligibility clarifications that may appear in the full text of the announcement. Overall, the IIRA can be summarized as a competitive DoD mechanism intended to fund well-supported, non-clinical-trial MS research ideas with strong justification and a clear path to advancing scientific understanding and/or improving MS patient care.Apply for W81XWH 22 MSRP IIRA
- The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Multiple Sclerosis, Investigator-Initiated Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on Apr 29, 2022.
- Applicants must submit their applications by Oct 03, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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| Funding Opportunity |
|---|
| DoD Multiple Sclerosis, Exploration-Hypothesis Development Award Apply for W81XWH 22 MSRP EHDA Funding Number: W81XWH 22 MSRP EHDA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| CWMD: Academic Research Initiative (ARI) Apply for WD ARI 22 001 Funding Number: WD ARI 22 001 Agency: Department of Homeland Security, Office of Procurement Operations - Grants Division Category: Science and Technology and other Research and Development Funding Amount: $300,000 |
| CWMD: Academic Research Initiative (ARI) Apply for DHS 22 CWMD 077 001 Funding Number: DHS 22 CWMD 077 001 Agency: Department of Homeland Security, Office of Procurement Operations - Grants Division Category: Science and Technology and other Research and Development Funding Amount: $300,000 |
| Natural Resources & Threatened Endangered Species Mgmt US Army Garrison Hawaii Oahu Apply for W9126G22 2 SOI 3024 Funding Number: W9126G22 2 SOI 3024 Agency: Department of Defense, Fort Worth District Category: Science and Technology and other Research and Development Funding Amount: $30,000,000 |
| Disaster Resilience Research Grants Apply for 22 593 Funding Number: 22 593 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: $400,000 |
| Leading Engineering for America's Prosperity, Health, and Infrastructure Apply for 22 594 Funding Number: 22 594 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: $2,000,000 |
| FY22 DEFENSE ESTABLISHED PROGRAM TO STIMULATE COMPETITIVE RESEARCH (DEPSCoR) – RESEARCH COLLABORATION (RC) Apply for FOA AFRL AFOSR 2022 0006 Funding Number: FOA AFRL AFOSR 2022 0006 Agency: Department of Defense, Air Force Office of Scientific Research Category: Science and Technology and other Research and Development Funding Amount: $600,000 |
| DOD Bone Marrow Failure Investigator-Initiated Research Award Apply for W81XWH 22 BMFRP IIRA Funding Number: W81XWH 22 BMFRP IIRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Bone Marrow Failure Idea Development Award Apply for W81XWH 22 BMFRP IDA Funding Number: W81XWH 22 BMFRP IDA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| FY22 DEFENSE ESTABLISHED PROGRAM TO STIMULATE COMPETITIVE RESEARCH (DEPSCoR) – CAPACITY BUILDING (CB) Apply for FOA AFRL AFOSR 2022 0007 Funding Number: FOA AFRL AFOSR 2022 0007 Agency: Department of Defense, Air Force Office of Scientific Research Category: Science and Technology and other Research and Development Funding Amount: $1,000,000 |
| DoD Combat Readiness Medical, Rapid Development and Translational Research Award Apply for W81XWH 22 S CRRP Funding Number: W81XWH 22 S CRRP Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| BJA FY 22 Justice Information Sharing Training and Technical Assistance (JIS TTA) Program Apply for O BJA 2022 171332 Funding Number: O BJA 2022 171332 Agency: Department of Justice, Bureau of Justice Assistance Category: Science and Technology and other Research and Development Funding Amount: $400,000 |
| DoD Vision, Translational Research Award Apply for W81XWH 22 VRP TRA Funding Number: W81XWH 22 VRP TRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Vision, Clinical Trial Award Apply for W81XWH 22 VRP CTA Funding Number: W81XWH 22 VRP CTA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Vision, Focused Translational Team Science Award Apply for W81XWH 22 VRP FTTSA Funding Number: W81XWH 22 VRP FTTSA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Vision, Investigator- Initiated Research Award Apply for W81XWH 22 VRP IIRA Funding Number: W81XWH 22 VRP IIRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Seasonal Natural and Cultural Resources Management Program Suppport on Air Force Installations Apply for W9126G 22 2 SOI 2923 Funding Number: W9126G 22 2 SOI 2923 Agency: Department of Defense, Fort Worth District Category: Science and Technology and other Research and Development Funding Amount: $1,309,000 |
| FY 22 DNA Capacity Enhancement for Backlog Reduction (CEBR) Program (Formula) Apply for O BJA 2022 171344 Funding Number: O BJA 2022 171344 Agency: Department of Justice, Bureau of Justice Assistance Category: Science and Technology and other Research and Development Funding Amount: $3,000,000 |
| Sedimentary Geology and Paleobiology Apply for 22 597 Funding Number: 22 597 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Hearing Restoration Focused Research Award Apply for W81XWH 22 HRRP FRA Funding Number: W81XWH 22 HRRP FRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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