Opportunity Information: Apply for RFA CA 19 063

This funding opportunity, RFA-CA-19-063, comes from the Department of Health and Human Services through the National Institutes of Health, specifically the National Cancer Institute (NCI). It supports revision applications to active NCI U24 cooperative agreement projects. In other words, it is not meant for brand-new standalone projects; it is designed for teams that already hold an NCI U24 award and want to request additional support to expand the scope of their ongoing work or speed up progress on the parent study. The key requirement is that the proposed expansion should incorporate informatics methods, tools, or resources that were developed with support from the NCI Informatics Technology for Cancer Research (ITCR) Program, either through current or prior ITCR funding.

The central goal is practical adoption and integration of ITCR-developed technologies into real cancer research settings. NCI is using this mechanism to encourage researchers to take informatics capabilities that already exist (for example, software tools, platforms, data standards approaches, analytic pipelines, or other computational resources created under ITCR) and apply them directly to active U24-supported cancer research efforts. The intent is to accelerate discovery by improving how data are collected, harmonized, analyzed, shared, or translated into research findings, while also reducing duplication of tool development across the field. Because these are cooperative agreements, recipients should expect substantial scientific involvement from NCI staff compared with a standard grant, which typically means closer coordination around milestones, deliverables, and project direction.

A major theme of the announcement is building new collaborations and strengthening interdisciplinary work. The revisions are meant to spur novel partnerships between teams running the parent U24 projects and investigators or groups associated with ITCR technologies. By incentivizing adoption, adaptation, and integration, NCI is signaling that it values not just inventing new informatics tools, but also proving their usefulness, improving their usability, and embedding them into the workflows of the relevant cancer research communities. The focus is on enabling cancer research and speeding scientific progress through informatics, with an emphasis on tangible improvements and broader community impact rather than purely exploratory development.

The award structure is a cooperative agreement (U24), and clinical trials are listed as optional, meaning the revision may include clinical trial-related components if appropriate, but a clinical trial is not required solely to be responsive. The opportunity sits in the Education and Health activity area and is associated with CFDA number 93.396. The funding details included an award ceiling of $100,000 and an expectation of about four awards, indicating relatively small, targeted supplements intended to catalyze specific expansions of scope rather than fund large new research programs.

Eligibility is broad in general government-grants terms and includes a wide range of domestic organization types, such as state, county, and local governments; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities; nonprofits with or without 501(c)(3) status; for-profit organizations (including small businesses); and other entities as described in the full eligibility language. Practically, though, the most important constraint is that applicants must be able to submit a revision to an existing, currently funded NCI U24 project, since the FOA is explicitly for revision applications tied to an active parent award rather than new applicants starting from scratch.

Key dates provided indicate the FOA was created on July 31, 2019, with an original closing date of November 20, 2019. While those dates reflect the specific historical solicitation window, the substantive takeaway is the program intent: a time-limited push to help active NCI U24 projects incorporate proven ITCR-supported informatics technologies, foster cross-team collaborations, and deliver accelerated, community-relevant gains in cancer research capability and productivity.

  • The Department of Health and Human Services, National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Revision Applications to Support the Application of Informatics Technology for Cancer Research (U24 Clinical Trials Optional)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.396.
  • This funding opportunity was created on Jul 31, 2019.
  • Applicants must submit their applications by Nov 20, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $100,000.00 in funding.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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